| Dimension | Scoring Notes | Score |
|---|---|---|
| Study Design | Primarily animal (rat) and in vitro studies. Same Khavinson group origin as Epitalon. Very limited human data — a few small observational reports in Russian literature. Animal/in vitro categorization is accurate. |
2 / 25 |
| Sample Size | No meaningful human intervention data. |
0 / 20 |
| Replication | Almost exclusively Khavinson/St. Petersburg Institute. Even more concentrated than Epitalon in terms of independent replication. |
2 / 20 |
| Journal Impact Factor | Published in Russian pharmacology and gerontology journals with minimal Western IF. Some papers in Bulletin of Experimental Biology and Medicine. |
4 / 15 |
| Funding Independence | Russian government/academic funded but single-institution dominance reduces confidence. |
1 / 10 |
| Population Diversity | Animal/in vitro. Not applicable. |
0 / 5 |
| Researcher h-Index | Same Khavinson group — moderate Russian database h-Index but lowest compound in catalog for evidence quality overall. |
1 / 5 |