| Dimension | Scoring Notes | Score |
|---|---|---|
| Study Design | Multiple human split-face RCTs and controlled trials for wrinkle reduction and skin firmness. Standard methodology for cosmeceutical research. |
20 / 25 |
| Sample Size | Individual trials typically 20-60 participants. Standard for cosmeceutical RCTs but small by pharmaceutical standards. |
12 / 20 |
| Replication | Some independent replication but a meaningful portion of trials funded or conducted by Sederma (developer). Independent academic replication exists but limited. |
8 / 20 |
| Journal Impact Factor | Published primarily in International Journal of Cosmetic Science (IF ~2), Journal of Cosmetic Dermatology (IF ~2-3), and Skin Pharmacology and Physiology. Mid-tier specialty journals. |
4 / 15 |
| Funding Independence | Significant Sederma involvement in research. Some independent dermatology trials, but developer funding is dominant in the evidence base. |
4 / 10 |
| Population Diversity | Studies predominantly female, mostly European or Asian populations. Moderate diversity within the cosmeceutical trial norm. |
1 / 5 |
| Researcher h-Index | Lead researchers in cosmeceutical space have moderate academic profiles. Not high-profile researchers by broader scientific standards. |
2 / 5 |