| Dimension | Scoring Notes | Score |
|---|---|---|
| Study Design | Human observational and some controlled trials primarily by Khavinson group (St. Petersburg Institute of Bioregulation). Studies in elderly populations for telomere length and aging biomarkers. No Western RCT. |
15 / 25 |
| Sample Size | Individual studies typically 30-80 elderly subjects. Small by modern standards. |
8 / 20 |
| Replication | Overwhelmingly single-institution — Vladimir Khavinson and St. Petersburg Institute of Bioregulation. This is the canonical single-institution replication case; same-institution multiple studies score 2/20. |
2 / 20 |
| Journal Impact Factor | Published in Bulletin of Experimental Biology and Medicine, Neuroendocrinology Letters. Low Western IF journals. |
1 / 15 |
| Funding Independence | Russian government and institute funded. Independent from commercial pharmaceutical industry. |
7 / 10 |
| Population Diversity | Elderly Russian populations. Reasonably diverse within elderly cohort but narrow geographic/ethnic base. |
3 / 5 |
| Researcher h-Index | Vladimir Khavinson has a notable h-Index within Russian gerontology literature (~30+ in Russian databases) but lower visibility in Western databases. Credible scientist within his field. |
3 / 5 |